Up-regulation of mir-133a-3p promotes ovary insulin resistance on granulosa cells of obese pcos patients via inhibiting pi3k/akt signaling

HIGHLIGHTS

• who: Xiaoman Yang from the All the GCs samples were collected from infertile patients treated with in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) treatment at the Center for Reproductive Medicine, the Affiliated Hospital of Shandong University of Traditional Chinese Medicine from November , to June A total of , PCOS patients were selected as PCOS group and , healthy women who were infertile because of fallopian tube factor or male factor were selected as the control group. According to the body mass index (BMI), PCOS group was divided into two sub-groups, with , cases (BMI u2265, ) in the . . .
  

   

  

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