New, potent, small molecule agonists of tyrosine kinase receptors attenuate dry eye disease

HIGHLIGHTS

  • who: Cintia S. de Paiva from the Duke University, United States have published the research: New, potent, small molecule agonists of tyrosine kinase receptors attenuate dry eye disease, in the Journal: (JOURNAL)
  • what: The authors use an experimental DED model to investigate the efficacies of novel small_molecule Trk agonists. The studies showed that C1 and pan eye drops increased Ptger4 mRNA and the corresponding protein expression in the cornea after desiccating stress reaching statistical significance for C1 in immunostained corneas.
  • how: Data were analyzed with a HyperScale architecture developed by ROSALIND Inc.2 . . .

     

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