The chemical structures and biological activities of indole diterpenoids

HIGHLIGHTS

  • who: Jingwen Niu from the (UNIVERSITY) have published the article: The chemical structures and biological activities of indole diterpenoids, in the Journal: (JOURNAL)

SUMMARY

    IDTs are a structurally diverse class of fungal secondary metabolites, all sharing a common core structure consisting of indole, and a diterpene carbon backbone derived from four mevalonate-derived isoprene units. Most of the IDTs are potent tremor mammalian mycotoxins, that also exhibit excellent biological activities, including cytotoxic, antibacterial, antiviral, and protein tyrosine phosphatase inhibitory activities. It was also found that while the methyl ester derivative of 11 was . . .

     

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