Optimization and antibacterial evaluation of novel 3-(5-fluoropyridine-3-yl)-2-oxazolidinone derivatives containing a pyrimidine substituted piperazine

HIGHLIGHTS

• who: Xin Wang and colleagues from the Department of Veterinary Medicine, Northeast Agricultural University, Harbin, China have published the paper: Optimization and Antibacterial Evaluation of Novel 3-(5-Fluoropyridine-3-yl)-2-oxazolidinone Derivatives Containing a Pyrimidine Substituted Piperazine, in the Journal: Molecules 2023, 28, 4267. of /2023/
• what: In this study series of novel were designed and synthesized based on compounds previously reported and their antibacterial activity was investigated.
• how: Preliminary screening results showed that all these compounds exhibited antibacterial activity against gram-positive bacteria including drug-sensitive strains and drug-resistant . . .
  

   

  

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