Interaction between chicken trim25 and mda5 and their role in mediated antiviral activity against ibdv infection

HIGHLIGHTS

• who: ufeffDoloresufeff ufeffRodru00edguezufeff from the China China China have published the research work: Interaction between chicken TRIM25 and MDA5 and their role in mediated antiviral activity against IBDV infection, in the Journal: (JOURNAL)
• what: To carry out this study the authors used IFN-u03b2 and NF-u0138B reporter assays in DF-1 cells co-transfected with chMDA5 Full or chMDA5 2CARD in combination with wild-type chTRIM25 or chTRIM25 C59S/C62S. The authors show that lower IFN-u03b2 and NF-kB promoter activation is achieved by overexpressing chMAVS in DF-1 TRIM25 KO cells compared . . .
  

   

  

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