Biochemical pathways of cellular mechanosensing/mechanotransduction and their role in neurodegenerative diseases pathogenesis

HIGHLIGHTS

  • who: Ilaria Tortorella and collaborators from the Department of Chemistry, Biology and Biotechnology, University of Perugia, Via del Giochetto have published the paper: Biochemical Pathways of Cellular Mechanosensing/Mechanotransduction and Their Role in Neurodegenerative Diseases Pathogenesis, in the Journal: Cells 2022, 3093 of /2022/
  • what: The authors recapitulate the general concepts of mechanobiology and the mechanisms that govern the mechanosensing and mechanotransduction processes and the authors examine the crosstalk between mechanical stimuli and intracellular biochemical response highlighting their effect on cellular organelles` homeostasis and dysfunction. The authors discuss how all these mechanisms converge towards the . . .

     

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