Programming multicellular assembly with synthetic cell adhesion molecules

HIGHLIGHTS

• who: Adam J. Stevens from the (UNIVERSITY) have published the research work: Programming multicellular assembly with synthetic cell adhesion molecules, in the Journal: (JOURNAL) of 28/Oct/2021
• what: The authors show that a wide array of synthetic cell adhesion molecules can be generated by combining orthogonal extracellular interactions with intracellular domains from native adhesion molecules, such as cadherins and integrins. The authors characterize the resulting cell-cell interfaces, and test whether synCAMs can program new multicellular organization.

SUMMARY

The resulting molecules yield customized cell-cell interactions with adhesion properties that . . .

 



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