Identification of lynch syndrome in patients with endometrial cancer based on a germline next generation sequencing multigene panel test

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SUMMARY

    For instance, patients may present with bloody stool in the case of colon cancer and vaginal bleeding in endometrial cancer, yet the cancer-associated symptom may not be apparent in cases of early-stage cancer, especially in certain types of cancers such as cancers of the ovary or pancreatobiliary tract. Endometrial cancer is likely to be the first cancer diagnosis for approximately half of patients with LS, preceding colon cancer by an average of 11 years. Making an effort to identify patients with LS among those diagnosed with endometrial cancer may be a starting . . .

     

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