HIGHLIGHTS
- who: Soudeh Ghafouri-Fard from the Universitu00e9 de Lille, France Jinan University, China have published the article: NLRP3: Role in ischemia/reperfusion injuries, in the Journal: (JOURNAL)
- future: Future studies are needed to find novel substances for amelioration of NLRP3-mediated I/R injuries.
SUMMARY
NLRP3 is expressed in smooth muscle cells, endothelial cells, beta cells and Frontiers in Immunology frontiersin.org 10.3389/fimmu.2022.926895 Activation of NLRP3 inflammasome needs a priming step that leads to up-regulation of NLRP3 and IL-1b in addition to NLRP3 post-translational . . .
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