HIGHLIGHTS
SUMMARY
Domain DOT1L lysine methyltransferase PRDM family, and the arginine methyltransferase PRMT family (Di Tullio et_al, 2022). Other HDMs containing JMJC structural domains, including KDM2 to 7, are iron- and 2ketoglutarate-dependent dioxygenases that can remove the methylation of H3K9me1/2, H3K27me1/2 and H4K20me1 associated with transcriptional silencing (Markolovic et_al, 2016; Yoo et_al, 2020). To better understand the specific functions of the DEGs, the authors performed Gene To develop an HMMR-related risk gene signature, the TCGA cohort was treated as the training set, and a GEO cohort Frontiers in Cell and Developmental Biology . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.