Plasminogen activator inhibitor 1 is not a major causative factor for exacerbation in a mouse model of sars-cov-2 infection

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  • who: Takashin Nakayama from the DepartmentKeio University Tokyo, u20118582, Japan have published the article: Plasminogen activator inhibitor 1 is not a major causative factor for exacerbation in a mouse model of SARS-CoV-2 infection, in the Journal: Scientific Reports Scientific Reports
  • how: The authors evaluated the effects of PAI-1 vaccine on thrombus formation in LPS-induced sepsis model in which suppressedfibrinolytic-type disseminated intravascular coagulation leads to microvascular thrombosis and subsequently impaired organ fu00ad unction33. The authors evaluated the effect of PAI-1 vaccine on survival and a severe systemic symptom (i.e . . .

     

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