HIGHLIGHTS
- who: Sierra S. Nishizaki from the Department of Human, University of Michigan, Ann Arbor, MI, USA have published the article: SEMplMe: a tool for integrating DNA methylation effects in transcription factor binding affinity predictions, in the Journal: (JOURNAL)
- what: DNA methylation is a key epigenetic mark known to act in a regulatory capacity, allowing transcription factors to bind in a cell-type specific manner.
SUMMARY
The effect of methylation on the binding of individual proteins has been studied in_vitro using protein binding microarrays (PBMs) and newer systematic enrichment of ligands by . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.