Deficiency of transcription factor nkx6.1 does not prevent insulin secretion in ins-1e cells

HIGHLIGHTS

• who: Vojtu011bch Pavluch from the Department have published the research work: Deficiency of transcription factor Nkx6.1 does not prevent insulin secretion in INS-1E cells, in the Journal: Scientific Reports Scientific Reports
• what: We confirmed that the transcription factor Nkx6.1 controls several metabolic genes, notably glucose transporter (Glut2) and pyruvate carboxylase (Pcx) genes and genes important for insulin biogenesis (Ero1lb and Slc30a8).
• how: The rates of GSIS obtained by linear regressions of data were calculated to be 101% u00b1 20% and 99% u00b1 30% for lines a and b of INS . . .
  

   

  

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