HIGHLIGHTS
- who: Yun-Jeong Kim from the (UNIVERSITY) have published the paper: TPX2 prompts mitotic survival via the induction of BCL2L1 through YAP1 protein stabilization in human embryonic stem cells, in the Journal: (JOURNAL) of 31/Oct/2022
- what: The authors propose that other cues to activate BCL2L1 promoter activity, such as YAP1 activation, would occur, leading to the acquisition of the survival advantage trait (e_g, YAP1 stabilization by Aurora A activity due to TPX2 induction).
- how: Considering the key roles of YAP1 in the survival of ESCs2425 the authors hypothesized that the activity . . .
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