New scaffolds of proteasome inhibitors: boosting anticancer potential by exploiting the synergy of in silico and in vitro methodologies

HIGHLIGHTS

• who: Romina A. Guedes and collaborators from the Research Institute for Medicines (iMedULisboa), Faculty of Pharmacy, University of Lisbon have published the article: New Scaffolds of Proteasome Inhibitors: Boosting Anticancer Potential by Exploiting the Synergy of In Silico and In Vitro Methodologies, in the Journal: Pharmaceuticals 2023, 1096 of /2023/
• what: The aim of this study was the discovery of novel scaffolds of with anticancer activity aiming to overcome the limitations of the existing Thus a structure-based virtual screening protocol was developed using the structure of the human 20S and 246 compounds from virtual . . .
  

   

  

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