Pictilisib-induced resistance is mediated through foxo1-dependent activation of receptor tyrosine kinases in mucinous colorectal adenocarcinoma cells

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  • who: Murali R. Kuracha et al. from the Department of Internal Medicine, University of Nebraska Medicine, Omaha, NE, USA have published the research work: Pictilisib-Induced Resistance Is Mediated through FOXO1-Dependent Activation of Receptor Tyrosine Kinases in Mucinous Colorectal Adenocarcinoma Cells, in the Journal: (JOURNAL) of 25/07/2023
  • what: The authors report that pictilisib-induced adaptive resistance is regulated by the FOXO-dependent rebound activity of receptor tyrosine kinases (RTKs) in mucinous colorectal adenocarcinoma (MCA) cells. The authors examined the consequence of FOXO1 nuclear localization in mucinous colorectal cancer cell lines associated with . . .

     

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