Mir-585-5p impedes gastric cancer proliferation and metastasis by orchestrating the interactions among creb1, mapk1 and mitf

HIGHLIGHTS

  • who: Yunwei Wang from the Jiaotong University, China have published the Article: MiR-585-5p impedes gastric cancer proliferation and metastasis by orchestrating the interactions among CREB1, MAPK1 and MITF, in the Journal: (JOURNAL)
  • what: This investigation demonstrated that MITF had a straight positive regulation of GC proliferative/metastatic properties. The authors report for the first time that miR-585-5p suppresses GC proliferative/metastatic properties by orchestrating the interactions among CREB1, MAPK1 and MITF. MiR-585-5p suppresses MITF activity by directly targeting MAPK1 Based on the previous prediction of MAPK1 as a target . . .

     

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