Development of a rapid lc-ms/ms method for simultaneous quantification of donepezil and tadalafil in rat plasma: its application in a pharmacokinetic interaction study after oral administration in rats

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  • who: Jiyoung Yoon and collaborators from the Department of Pharmaceutical Biochemistry, College of Pharmacy, Hee University, Seoul, Republic of Korea have published the Article: Development of a Rapid LC-MS/MS Method for Simultaneous Quantification of Donepezil and Tadalafil in Rat Plasma: Its Application in a Pharmacokinetic Interaction Study after Oral Administration in Rats, in the Journal: Molecules 2023, 28, 2352. of /2023/
  • what: This study provided the first preliminary evidence of non-significant DDI between DPZ and TAD based on PK profiles in rats.
  • how: The stability of the plasma analytes was . . .

     

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