Development of a patient-derived 3d immuno-oncology platform to potentiate immunotherapy responses in ascites-derived circulating tumor cells

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  • who: Thomas J. Gerton and collaborators from the Division of Women`s and Perinatal Pathology, Department of Pathology, Brigham and Women`s Hospital, Harvard Medical School, Boston, MA, USA have published the paper: Development of a Patient-Derived 3D Immuno-Oncology Platform to Potentiate Immunotherapy Responses in Ascites-Derived Circulating Tumor Cells, in the Journal: (JOURNAL)
  • what: This study shows that epigenetic priming potentiates ICB responses in tumor models and ex vivo 3D patient-derived platforms. The authors report the optimization of a 3D immuno-oncology PDOTS platform for ex vivo screening of HGSOC-derived . . .

     

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