HIGHLIGHTS
- who: Qiuyun Xu from the United States Department of Immunology, School of Medicine, Nantong University, Nantong, China have published the Article: Inflammasome-targeting natural compounds in inflammatory bowel disease: Mechanisms and therapeutic potential, in the Journal: (JOURNAL)
- how: Their data showed that oroxindin can suppress macrophage infiltration to the colon and attenuated colon pathological changes. The data showed that polysaccharides from DO (DOPS) can inhibit b-arrestin1 expression and suppress activation of the NLRP3 inflammasome in both in_vivo and in_vitro experiments.
- future: The authors give an overview of these studies discuss the cellular . . .
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