The srebp-dependent regulation of cyclin d1 coordinates cell proliferation and lipid synthesis

HIGHLIGHTS

  • who: Arwa Aldaalis from the University of Rome Tor Vergata, Italy have published the research: The SREBP-dependent regulation of cyclin D1 coordinates cell proliferation and lipid synthesis, in the Journal: (JOURNAL)
  • what: The authors propose that the SREBPdependent regulation of cyclin D1 helps coordinate cell cycle progression with increased lipid synthesis to support cancer cell growth. signaling as a result of AKT-mediated inactivation of GSK-3 , and the authors have proposed that this could contribute to the accumulation of nuclear SREBP1c seen in response insulin treatment. The aim of this study was to . . .

     

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