Effects of omecamtiv mecarbil on the contractile properties of skinned porcine left atrial and ventricular muscles

HIGHLIGHTS

  • who: Ca and colleagues from the Florida State University, United States have published the research work: Effects of omecamtiv mecarbil on the contractile properties of skinned porcine left atrial and ventricular muscles, in the Journal: (JOURNAL)
  • what: The authors investigated the effects of OM in the clinically relevant concentration range (i.e., 0.5 and 1.0 u03bcM; see Teerlink et_al, 2011, 2016) on steady-state contractile properties in skinned porcine left ventricular (PLV) and atrial (PLA) muscles. This is similar to the earlier finding using bovine left ventricular muscle (Fukuda et_al, 1998), but slightly . . .

     

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