Detection of antibodies against the huntingtin protein in human plasma

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  • who: Hu00e9lu00e8na L. Denis from the Laboratory of Neurodegenerative Diseases, Institut Franu00e7ois Jacob, MIRCen, CEA, CNRS, Fontenayu2011Auxu2011Roses, France have published the Article: Detection of antibodies against the huntingtin protein in human plasma, in the Journal: (JOURNAL)
  • what: The authors assessed the presence and titer of antibodies recognizing HTT/mHTT in patients with HD (n = 66) and age- and gender-matched healthy controls (n = 66) using a combination of Western blotting and ELISA. This analysis demonstrated a complex relationship between disease severity and antibody titers for mHTT and HTT/mHTTExon1. This study provides evidence that antibodies . . .

     

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