The role of genetic predisposition in cardiovascular risk after cancer diagnosis: a matched cohort study of the uk biobank

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  • who: Huazhen Yang from the Genetic factors have been demonstrated to play an important role in the development of CVD [14]For instance, using data from twins, a Danish study reported more pronounced risk of stroke hospitalisation and stroke death among monozygotic co-twins compared with dizygotic co-twins, indicating that genetic factors increase the risk of stroke [15]. Also, genome-wide association studies (GWAS) have identified many genetic variants (i.e. singlenucleotide polymorphisms [SNPs]), such as rs, within BCAS3, rs, near TSPAN2, and rs, near CASZ1, that associated with risk of coronary disease [16], atrial fibrillation . . .

     

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