HIGHLIGHTS
- who: Hepatocytes and colleagues from the Institute for System Dynamics, University of Stuttgart, Stuttgart, Germany, Department of Pharmaceutical Biology and Biotechnology, Albert Ludwigs University have published the article: Modeling the TNF a -Induced Apoptosis Pathway in Hepatocytes, in the Journal: (JOURNAL) of April/20,/2011
- what: NF-kB activation is the main reason why TNFa alone does not primarily lead to hepatocyte apoptosis. Since this model is used as initial point for the study the authors will describe it shortly. Fas ligand does not induce cytochrome c release from the mitochondria in the sensitizing model . . .
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