HIGHLIGHTS
- who: August and collaborators from the Boston, United States have published the paper: Dihydropyridine-derived calcium channel blocker as a promising anti-hantavirus entry inhibitor, in the Journal: (JOURNAL)
- what: This study demonstrated that benidipine HCl has a powerful antiviral effect on HTNV in a variety of cells with an IC50 at a low micromolar level.
- future: Research is necessary to identify the specific mechanism.
SUMMARY
During virus maturation, GPC is cleaved into Gn and Gc by the host enzyme, and this cleavage facilitates virus attachment to cellular receptors . . .
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