HIGHLIGHTS
- who: Stefan Milde and Guy C. Brown from the (UNIVERSITY) have published the research work: Knockout of the P2Y6 Receptor Prevents Peri-Infarct Neuronal Loss after Transient, Focal Ischemia in Mouse Brain, in the Journal: (JOURNAL)
- what: The authors show evidence here from a small trial that the knockout of the P2Y6 receptor required for microglial phagocytosis of neurons the delayed after transient focal brain ischemia induced by endothelin-1 injection in mice.
- how: To test whether blocking microglial phagocytosis can prevent neuronal loss in peri-infarct areas after stroke the authors conducted . . .
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