Structure of the native sec61 protein-conducting channel

HIGHLIGHTS

  • who: Stefan Pfeffer from the Biochemistry, Gene Center and Center for integrated Protein Science Munich, University of Munich, Munich, Germany, Department of Medical have published the research: Structure of the native Sec61 protein-conducting channel, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS of 28/09/2015
  • how: For structure determination of the ribosome-bound translocon in its native membrane environment the authors applied CET and subtomogram analysis to rER vesicles isolated from canine pancreas.

SUMMARY

    The structure of the prokaryotic Sec61 homologue, the SecY complex, has been extensively studied by X . . .

     

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