Regulation of very-long acyl chain ceramide synthesis by acyl-coa-binding protein

HIGHLIGHTS

• who: Natalia Santos Ferreira from the (UNIVERSITY) have published the research: Regulation of very-long acyl chain ceramide synthesis by acyl-CoA-binding protein, in the Journal: (JOURNAL) of March/19,/2017
• what: The authors show that acyl-coenzyme A-binding protein (ACBP) potently facilitates very-long acyl chain ceramide synthesis. The authors show that ACBP interacts with CerS2 and CerS3. The authors now show for the first time that ACBP potently activates CerS2 and CerS3 activity via direct interaction, and the authors show that ACBP ablation has deleterious effects on SL levels in mouse . . .
  

   

  

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