Procollagen c-proteinase enhancer-1 (pcpe-1) deficiency in mice reduces liver fibrosis but not nash progression

HIGHLIGHTS

• who: Patricia Sansilvestri Morel and colleagues from the Universidad de Navarra, IdiSNA and CIBERCV, Pamplona, Spain, Cardiovascular and Metabolic Diseases have published the Article: Procollagen C-Proteinase Enhancer-1 (PCPE-1) deficiency in mice reduces liver fibrosis but not NASH progression, in the Journal: PLOS ONE of January/28,/2022
• what: This study explores the role of PCPE-1 in the development of NASH and liver fibrosis. To better understand from a mechanistic standpoint, the impact of Pcolce gene deficiency on NASH progression and fibrosis, gene_expression studies focusing on key relevant pathways were performed.
 



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