HIGHLIGHTS
- who: Andrea Errico and collaborators from the Department of Surgery, Oncology and Gastroenterology, Veneto Institute of Oncology IOV-IRCCS, Department of Biomedical Sciences, University of Padova, Padova, Italy have published the Article: Neurofibromin Deficiency and Extracellular Matrix Cooperate to Increase Transforming Potential through FAK-Dependent Signaling, in the Journal: (JOURNAL)
- what: The authors assess the hypothesis that neoplastic transformation of neurofibroma SC requires both growth-factor signaling and matrix signaling contributed by FAK. The aim of this experimental system is to mimic in_vitro as close as possible the Pnfs' ECM, which is typically fibrotic. The . . .
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