HIGHLIGHTS
- who: Olivia A. Diaz Arguello and Hidde J. Haisma from the Department of Chemical and Pharmaceutical Biology, Groningen Research Institute of Pharmacy have published the article: Apoptosis-Inducing TNF Superfamily Ligands for Cancer Therapy, in the Journal: Cancers 2021, 1543 of /2021/
- what: The majority of them faltered in the first stages of the studies, showing a lack of effectiveness.
- how: A fusion_protein composed of an scFv antibody from the high-molecular-weight melanoma-associated glycoprotein gp240 (ScFvMEL) and TNF-α known as scFvMEL/TNF was tested in murine models to assess the therapeutic . . .
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