Type i-f crispr-cas resistance against virulent phages results in abortive infection and provides population-level immunity

HIGHLIGHTS

  • who: Bridget N. J. Watson from the University of have published the research: Type I-F CRISPR-Cas resistance against virulent phages results in abortive infection and provides population-level immunity, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • what: The authors examine the outcome of CRISPR-Cas immunity using Pectobacterium atrosepticum, which carries a type I-F system, and two unrelated virulent phages as model systems. Instead, the authors propose that CRISPR-Cas immunity still enables a window of time for the virulent phage to express toxic products or takeover host resources and machinery18. The . . .

     

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