A multisubstrate reductase from plantago major: structure-function in the short chain reductase superfamily

HIGHLIGHTS

  • who: from the (UNIVERSITY) have published the research: A multisubstrate reductase from Plantago major: structure-function in the short chain reductase superfamily, in the Journal: (JOURNAL) of 13/03/2018

SUMMARY

    The crystal_structures of PmMOR wild_type and PmMOR mutants in complex with NADP+ or NAD+ and either 8-oxogeranial, citral or progesterone help to reveal the substrate specificity determinants and catalytic machinery of the protein. Although a complete genome of P. major is not yet available, an EST database is accessible and a gene annotated as a 5ß-POR was identified (ADG56541.1 . . .

     

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