Novel simple conjugation chemistries for decoration of gmma with heterologous antigens

HIGHLIGHTS

  • who: Roberta Di Benedetto et al. from the GSK Vaccines Institute for Global Health (GVGH), Via Fiorentina, Siena, Italy have published the article: Novel Simple Conjugation Chemistries for Decoration of GMMA with Heterologous Antigens, in the Journal: (JOURNAL) of 31/08/2021
  • what: Chemical conjugation represents a tool for linking antigens also from phylogenetically distant pathogens to Here the authors develop two simple and widely applicable conjugation chemistries targeting proteins or lipopolysaccharides on the surface of Generalized Modules for Membrane Antigens (GMMA) spontaneously released from Gram-negative bacteria mutated to increase vesicle yield and reduce . . .

     

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