Apc-targeted dna vaccination against reticulocyte-binding protein homolog 5 induces plasmodium falciparum-specific neutralizing antibodies and t cell responses

HIGHLIGHTS

• who: Louise Bjerkan from the National Institute of Allergy and of Health (NIH), United States , Institute of Clinical Medicine, University of Oslo and Oslo University Hospital, Oslo, Norway, Jenner Institute, University of have published the article: APC-Targeted DNA Vaccination Against Reticulocyte-Binding Protein Homolog 5 Induces Plasmodium falciparum-Specific Neutralizing Antibodies and T Cell Responses, in the Journal: (JOURNAL)
• what: The authors report a novel vaccination strategy against the merozoite form of malaria. Intramuscular vaccination with scFvaMHCII-PfRH5DNL in this study induced significantly higher PfRH5FL-specific IgG1 levels as compared to non-targeted control . . .
  

   

  

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