Hypoxia-inducible factors as key players in the pathogenesis of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis

HIGHLIGHTS

• who: Andrew J. Murray from the Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom have published the research work: Hypoxia-Inducible Factors as Key Players in the Pathogenesis of Non-alcoholic Fatty Liver Disease and Non-alcoholic Steatohepatitis, in the Journal: (JOURNAL)
• future: Work is required to determine whether HIF2α activation in NAFLD leads to lower FAO in animal models and human patients especially in the absence of imposed hypoxia though current evidence suggests that HIF2α activation in NAFLD contributes to hepatic steatosis and that HIF2α activation can limit fatty_acid oxidation . . .
  

   

  

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