Biogenic selenium nanoparticles alleviate intestinal epithelial barrier damage through regulating endoplasmic reticulum stress-mediated mitophagy

HIGHLIGHTS

  • who: Lei Qiao et al. from the The Key Laboratory for Space Bioscience and Biotechnology, School of Life Sciences, Northwestern Polytechnical University, Xi'an, Shaanxi, China have published the research work: Biogenic Selenium Nanoparticles Alleviate Intestinal Epithelial Barrier Damage through Regulating Endoplasmic Reticulum Stress-Mediated Mitophagy, in the Journal: Oxidative Medicine and Cellular Longevity of 31/03/2022
  • what: Oxidative stress induces the disruption of the intestinal TJ barrier and the increase of intestinal epithelial permeability and Ca2+ concentration in the cytoplasm, which is partly attributed to the enhanced ERS and mitophagy via the inhibition . . .

     

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