HIGHLIGHTS
- who: Angela Deyà-Martínez from the (UNIVERSITY) have published the article: Impact of JAK Inhibitors in Pediatric Patients with STAT1 Gain of Function (GOF) Mutations—10 Children and Review of the Literature, in the Journal: (JOURNAL)
- what: The main reasons to start JAK inhibition were immune dysregulation (10/10), manifested as oral aphthae, keratitis, enteropathy and autoimmune hepatitis, followed by uncontrolled CMC (6/10). Although specific information was not available for all previously published cases the main reason to start treatment were autoimmune complications. The study provides a detailed description of the clinical experience . . .
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