Structure and possible function of a g-quadruplex in the long terminal repeat of the proviral hiv-1 genome

HIGHLIGHTS

• who: Beatrice De Nicola and colleagues from the School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore and , Department of Molecular Medicine, University of Padua, Italy have published the Article: Structure and possible function of a G-quadruplex in the long terminal repeat of the proviral HIV-1 genome, in the Journal: (JOURNAL) of November/16,/2015
• what: The authors report the structure of a biologically relevant G-quadruplex within the LTR promoter region of HIV-1. Considering the dramatic effects of incorporating a single G18T base mutation on the HIV-1 promoter activity . . .
  

   

  

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