Cyclin b1 is essential for mitosis in mouse embryos, and its nuclear export sets the time for mitosis

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  • who: Bernhard Strauss and colleagues from the Gurdon Institute, Cambridge, England, UK University of have published the paper: Cyclin B1 is essential for mitosis in mouse embryos, and its nuclear export sets the time for mitosis, in the Journal: (JOURNAL) of 01/09/2022
  • what: The authors show that Cyclin B1-/- embryos arrest in G2 phase after just two divisions. In contrast to studies transfecting Cyclin B1 and Cdk1AF into human cells (Jin et_al, 1998), the experiments showed that constitutively nuclear Cyclin B1 had little effect on the duration of mitosis (Fig 6 A), nor . . .

     

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