Radiolabelled polymeric iga: from biodistribution to a new

HIGHLIGHTS

  • who: Top from the Nuclear Medicine Department, Dupuytren University Hospital, Limoges, France have published the research work: Radiolabelled polymeric IgA: from biodistribution to a new, in the Journal: (JOURNAL)
  • what: By radiolabelling monomeric (m) and polymeric (p) IgA with technetium 99m (99mTc) this study assessed IgA biodistribution and tumour-targeting potency. By radiolabelling with 99mTc, the authors report the natural pharmacokinetic and biodistribution of different isotypes of antibodies, IgA directed against CEA, compared with IgG in healthy mice and in a xenograft mouse model of human colon carcinoma.
  • how: This result is consistent . . .

     

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