Engineered lactococcus lactis secreting il-23 receptor-targeted rex protein blockers for modulation of il-23/th17-mediated inflammation

HIGHLIGHTS

  • who: Tina Vida Plavec and colleagues from the Department of Biotechnology, Jožef Stefan Institute, Jamova, Ljubljana, SloveniaFaculty of Pharmacy, University of Ljubljana, Aškerčeva, Ljubljana, Slovenia have published the research work: Engineered Lactococcus lactis Secreting IL-23 Receptor-Targeted REX Protein Blockers for Modulation of IL-23/Th17-Mediated Inflammation, in the Journal: (JOURNAL)
  • what: The authors aimed to engineer recombinant L lactis cells producing/secreting REX binding proteins that have been described as IL-23 receptor (IL-23R) blockers and IL-23R antagonists suppressing the secretion of cytokine IL-17A a pivotal . . .

     

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