Expression of mmp-2 and timp-1 in renal tissue of patients with chronic active antibody-mediated renal graft rejection

HIGHLIGHTS

• who: Interstitial fibrosis et al. from the AMRAmong them , were males (age , ± , years) and , were females (age , ± , years). The duration after kidney transplantation were, years (mean time of, ., years), the mean level of serum creatine was±μmol/, h urinary protein >0.5g/24h and urinary protein (1+, +). The triple immunosuppressant treatment protocol was cyclosporine + mycophenolate mofetil + prednisone in , patients and tacrolimus + mycophenolate mofetil + prednisone in , patients and sirolimus + mycophenolate mofetil + prednisone in , patient. Before renal biopsy, color doppler ultrasound detection in renal allografts and serum drug concentration test were performed to exclude acute rejection, nephrotoxicity of immunosuppressant . . .
  

   

  

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