Nmr structure of the human prion protein with the pathological q212p mutation reveals unique structural features

HIGHLIGHTS

  • who: Pathological Q and colleagues from the Chemistry, Warsaw University, Warsaw, Poland, SISSA Unit, Italian Institute of Technology, Trieste, Italy, Faculty of Chemistry and Chemical Technology, University of have published the research work: NMR Structure of the Human Prion Protein with the Pathological Q212P Mutation Reveals Unique Structural Features, in the Journal: (JOURNAL) of July/22,/2010
  • what: To provide new clues on the role of pathological point mutations on PrP structure, in this study the authors determined and examined a high-resolution 3D structure of the truncated recombinant HuPrP(90-231) containing the pathological . . .

     

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