Metformin modulates innate immune-mediated inflammation and early progression of nafld-associated hepatocellular carcinoma in zebrafish

HIGHLIGHTS

  • who: Sofia de Oliveira from the University of WisconsinUniversity of Wisconsin-Madison, Madison, United States have published the paper: Metformin modulates innate immune-mediated inflammation and early progression of NAFLD-associated hepatocellular carcinoma in zebrafish, in the Journal: (JOURNAL)
  • what: The authors focused the study on the early progression phase of HCC and used 13 days post-fertilization (dpf) Tg (fabp10a:pt-b-cat) larvae, with or without a liver marker, Tg(fabp10a:egfp) or Tg(fabp10a: h2bmCherry), referred to here as HCC larvae . These findings are consistent with previous reports showing increased angiogenesis in . . .

     

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