Robo2 contains a cryptic binding site for neural egfl-like (nell) protein 1/2

HIGHLIGHTS

  • who: Naoka Yamamoto from the (UNIVERSITY) have published the article: Robo2 contains a cryptic binding site for neural EGFL-like (NELL) protein 1/2, in the Journal: (JOURNAL) of September/13,/2018
  • what: The authors carried out a comprehensive analysis of the interaction between NELL1 and the Robo family of receptors and demonstrated that Robo2 contains a cryptic binding_site for both NELL1 and NELL2. Because NELL1 binds to the first FNIII domain of both Robo2 and Robo3, the authors focused on identifying amino_acid residues that only differ between Robo1 and Robo2/3.
  • how . . .

     

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