HIGHLIGHTS
- who: Chuanwu Xia from the (UNIVERSITY) have published the research work: Conformational Changes of NADPH-Cytochrome P450 Oxidoreductase Are Essential for Catalysis and Cofactor Binding*, in the Journal: (JOURNAL) of February/13,/2011
- how: All data were collected using an R-AXIS IV2⫹ detector system with a Micromax 007 generator. This result is comparable with that obtained with human CYPOR (k ⫽ 12 ⫾ 0.4 s⫺1) .
SUMMARY
A second electron is delivered to the oxyferrous P450, forming a peroxo species (Fe3⫹OO2⫺), which rapidly and irreversibly proceeds through the catalytic cycle . . .
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