Average rank-based score to measure deregulation of molecular pathway gene sets

HIGHLIGHTS

  • who: Huan Yang and collaborators from the Department of Reproductive Endocrinology, Obstetrics and Gynecology Hospital, Fudan University, Shanghai, China, Program in Computational Biology and have published the paper: Average Rank-Based Score to Measure Deregulation of Molecular Pathway Gene Sets, in the Journal: (JOURNAL) of July/18,/2011
  • what: The authors propose a novel statistic named AR-score (average rank based score) to measure pathway activities based on microarray gene expression profiles. In practice, the method the authors propose here can also be readily applied to other gene_expression data for better understanding relevant biological problems . . .

     

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