From dynamic expression patterns to boundary formation in the presomitic mesoderm

HIGHLIGHTS

• who: Hendrik B. Tiedemann et al. from the Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany, Kinesis Pharma BV, NKEditor: David KLubensky, University of Michigan, United States of America have published the article: From Dynamic Expression Patterns to Boundary Formation in the Presomitic Mesoderm, in the Journal: (JOURNAL) of June/28,/2012
• what: The authors propose a cell- and gene-based computer model for mammalian somitogenesis, simulating a gene_regulatory_network combining clock (Hes1/7) and gradient (Tbx6, Fgf8, Wnt3a) with Delta/Notch signaling resulting in dynamic gene_expression patterns . . .
  

   

  

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